Thyroid-stimulating hormone (TSH), or thyrotropin, is produced by the pituitary gland to regulate the thyroid gland’s production of Thyroid hormones T3 and T4 which are released into the bloodstream.

If you have TSH is higher than normal range (between 0.45 – 4.5 mIU/L), the thyroid gland fails to produce enough thyroid hormones (T3 and T4).

The pituitary gland, located at the base of the brain, monitors the levels of thyroid hormones in the blood. If these Thyroid hormone levels are low, as in hypothyroidism, the pituitary gland increases the production of TSH to stimulate the thyroid gland to produce more thyroid hormones.

So if you have a high TSH Level, it Indicates an underactive thyroid, and you may have hypothyroidism.